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Renal and perirenal space involvement in acute pancreatitis: An MRI study

Xing Hui Li1, Xiao Ming Zhang, Yi Fan Ji

  • 1Sichuan Key Laboratory of Medical Imaging, Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China. lixinghui1005@126.com

European Journal of Radiology
|May 23, 2012
PubMed
Abstract

Insights

Perirenal space abnormalities are common in acute pancreatitis (AP) and correlate with disease severity. Renal apparent diffusion coefficient (ADC) values indicate kidney injury in AP patients.

Area of Science:

  • Radiology
  • Gastroenterology
  • Nephrology

Background:

  • Acute pancreatitis (AP) can lead to renal complications.
  • Assessing renal and perirenal space involvement in AP is crucial for understanding disease severity and potential kidney injury.

Purpose of the Study:

  • To investigate the prevalence and characteristics of renal and perirenal space involvement in AP using MRI.
  • To determine the relationship between these findings and AP severity, as well as kidney function.

Main Methods:

  • Retrospective analysis of 115 AP patients who underwent MRI.
  • MRI sequences included conventional and diffusion-weighted imaging (DWI).
  • Renal apparent diffusion coefficient (ADC) and MR severity index (MRSI) were measured/calculated. Kidney function tests were performed.

Main Results:

  • Perirenal space abnormalities (e.g., thickened renal fascia, perirenal stranding/fluid) were highly prevalent (99%, 62%, 40%).
  • Prevalence of perirenal space involvement correlated positively with AP severity (MRSI).
  • Lower renal ADC values were observed in patients with abnormal kidney function. Kidney function abnormalities increased with AP severity (9.4% mild, 32% moderate, 100% severe).

Conclusions:

  • Perirenal space involvement is significantly more common than renal parenchymal involvement in AP.
  • MRI-detected perirenal space involvement positively correlates with AP severity.
  • Renal ADC values and the prevalence of kidney dysfunction are linked to AP severity.

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