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A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
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Published on: April 2, 2012

Necrodestructive herpes zoster.

Sanjeev Gupta1, Sunita Gupta, Kamal Aggarwal

  • 1Department of Dermatology and STI, MM Institute of Medical Sciences and Research, Mullana, Ambala, India.

Indian Journal of Dermatology
|May 23, 2012
PubMed
Summary
This summary is machine-generated.

Herpes Zoster (HZ) can cause severe scarring, even in immunocompetent individuals. This case highlights debilitating nasal scarring from HZ affecting the ophthalmic nerve, leading to airway obstruction.

Keywords:
Elderlyherpes zosterimmunocompetentnecrodestructive

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Area of Science:

  • Dermatology
  • Ophthalmology
  • Virology

Background:

  • Herpes Zoster (HZ), caused by the Varicella zoster virus, typically resolves without lasting skin damage.
  • While scarring and pigment changes are more common in immunocompromised patients, they can occur in others.

Purpose of the Study:

  • To report a rare case of severe nasal scarring and obstruction caused by Herpes Zoster in an immunocompetent elderly female.
  • To emphasize the potential for significant disfigurement and functional impairment from HZ, even in healthy individuals.

Main Methods:

  • Case report of an elderly, immunocompetent female diagnosed with Herpes Zoster.
  • Clinical examination and documentation of HZ lesions involving the ophthalmic division of the trigeminal nerve, including the nasociliary branch.
  • Assessment of scarring and nasal obstruction resulting from the cutaneous lesions.

Main Results:

  • The patient experienced HZ infection affecting the ophthalmic division of the trigeminal nerve.
  • Cutaneous lesions on the nose resulted in severe, mutilating scarring.
  • The scarring led to complete obstruction of the right anterior naris.

Conclusions:

  • Herpes Zoster can lead to severe scarring and functional compromise, such as airway obstruction, even in immunocompetent individuals.
  • Ophthalmic division HZ, particularly involving the nasociliary branch, carries a risk of significant facial disfigurement and complications.
  • This case underscores the importance of recognizing and managing HZ complications beyond typical skin healing.