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Updated: May 22, 2026

Studying Murine Small Bowel Mechanosensing of Luminal Particulates
Published on: March 18, 2022
[Preliminary study on simulating sensory nerves of intestinal contents using ultrasound detecting system]
Jianguo Li1, Zonghai Huang, Fujun Shi
1Department of General Surgery, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, China.
Abstract:
Successful assessing intestinal lumen content with ultrasound signals might lay a strong basis for the development of the artificial anal sphincter. In the present study, we utilized a modified MLU02-212 ultrasonic gas bubble detector to test the distal part of proximal colon in each rabbit, for the group of twenty healthy New Zealand rabbits. Voltage signals of solid, liquid, gas and empty content of the lumen were collected and compared. The results indicated that there were significant differences among the voltage signals in the 4 conditions (P = 0.000), respectively. Multiple comparison showed significant differences existed in any pair of the four conditions (P = 0.000). Three signal non-overlapping regions existed in these 4 conditions. Thus it seemed that ultrasound could be utilized to distinguish various contents inside the intestinal lumen and could act as "artificial sensory nerve".
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