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Related Concept Videos

Spanning Openings in Brick Walls01:20

Spanning Openings in Brick Walls

In brick wall construction, supporting structures are crucial for openings like windows and doors to maintain the integrity and support the weight of the wall above. These supports include lintels, corbels, and arches, each serving specific structural purposes.
Lintels are primary supports used to span openings and can be crafted from materials such as reinforced concrete, steel-reinforced brick masonry, or simple steel angles. These are straightforward to install and are typically concealed...
Gap Junctions01:37

Gap Junctions

Multicellular organisms employ a variety of ways for cells to communicate with each other. Gap junctions are specialized proteins that form pores between neighboring cells in animals, connecting the cytoplasm between the two, and allowing for the exchange of molecules and ions. They are found in a wide range of invertebrate and vertebrate species, mediate numerous functions including cell differentiation and development, and are associated with numerous human diseases, including cardiac and...
Gap Junctions01:27

Gap Junctions

The cytoplasm of adjacent animal cells can exchange small molecules, ions, and secondary messengers via the communication channels which form the gap junctions. These junctions comprise a few hundred to thousands of molecular channels, each made of two halves, called the connexon hemichannel. A connexon is a hexamer of six transmembrane connexin proteins, which assemble radially, thus forming a pore or channel in the center. One connexon hemichannel docks with a corresponding connexon on the...
Contact-dependent Signaling01:19

Contact-dependent Signaling

Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
Long-patch Base Excision Repair01:02

Long-patch Base Excision Repair

Since the discovery of the two BER pathways, there has been a debate about how a cell chooses one pathway over the other and the factors determining this selection. Numerous in vitro experiments have pointed out multiple determinants for the sub-pathway selection. These are:
Support Reactions01:30

Support Reactions

A coplanar force system refers to a set of forces that all lie in the same plane and are subject to different reactions between the point of contact and the supports. Understanding how different types of supports affect coplanar forces is crucial for designing safe and reliable structures that can withstand external loads.
The purpose of the supports is to prevent the translational motion of the system by applying an equal and opposite force and to prevent the system's rotation by applying a...

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Related Experiment Video

Updated: May 22, 2026

A Neural Implant Design Toolbox for Nonhuman Primates
06:33

A Neural Implant Design Toolbox for Nonhuman Primates

Published on: February 9, 2024

Plugging a gap in support.

Antonia Dean, Tara Beaumont

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |May 24, 2012
    PubMed
    Summary

    Patients with secondary breast cancer need more support, as current treatment and care are often insufficient. National Health Service (NHS) and voluntary organizations must improve outreach to these individuals.

    Area of Science:

    • Oncology
    • Patient Support Services
    • Healthcare Management

    Background:

    • Secondary breast cancer patients often undergo prolonged treatments.
    • These patients require substantial and continuous support.
    • Existing evidence suggests current care and treatment are inadequate.

    Purpose of the Study:

    • To highlight the inadequate treatment and care for secondary breast cancer patients.
    • To emphasize the need for enhanced support services.
    • To call for improved reach from the NHS and voluntary sector.

    Main Methods:

    • Review of existing evidence on secondary breast cancer patient care.
    • Analysis of support levels and treatment adequacy.
    • Identification of gaps in healthcare and voluntary sector services.

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    Last Updated: May 22, 2026

    A Neural Implant Design Toolbox for Nonhuman Primates
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    10:32

    Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

    Published on: June 3, 2020

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    Main Results:

    • Patients with secondary breast cancer face continuous treatment demands.
    • Significant deficiencies exist in the current treatment and care provision.
    • There is a clear need for increased engagement from healthcare and support organizations.

    Conclusions:

    • Current care for secondary breast cancer is insufficient.
    • Enhanced support and improved treatment accessibility are crucial.
    • The NHS and voluntary sector must increase efforts to support these patients.