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High frequency of overlap between functional dyspepsia and overactive bladder
J Matsuzaki1, H Suzuki, Y Fukushima
1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
Neurogastroenterology and Motility
|May 24, 2012
Summary
Overactive bladder syndrome (OAB) is common in patients with functional dyspepsia (FD), even without irritable bowel syndrome (IBS). Managing OAB symptoms is crucial for improving the quality of life for individuals with FD.
Area of Science:
- Gastroenterology
- Urology
- Public Health
Background:
- Overactive bladder syndrome (OAB) is characterized by urgency, with or without urge incontinence, frequency, and nocturia.
- Irritable bowel syndrome (IBS) has known associations with bladder symptoms.
- The relationship between functional dyspepsia (FD) and OAB requires further investigation.
Purpose of the Study:
- To determine the prevalence and overlap of OAB in individuals with FD.
- To explore the association between FD and OAB, independent of IBS.
- To assess if subtypes of FD (PDS, EPS) influence OAB prevalence.
Main Methods:
- A web-based survey was administered to 5494 participants.
- Data collected included symptoms of OAB, FD, IBS, and demographic information.
- Prevalence and odds ratios were calculated to examine associations.
Main Results:
- 20.5% of participants with FD also had OAB (OR: 2.85).
- OAB was highly prevalent in individuals with FD, with or without IBS (OR: 3.09 without IBS).
- Concomitant FD and IBS showed a stronger association with OAB (OR: 4.34).
Conclusions:
- OAB is common in patients with FD, irrespective of IBS.
- Dyspeptic symptoms correlate with increased OAB symptom severity.
- Addressing OAB is important for enhancing the quality of life in FD patients.
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