Related Experiment Video

Updated: May 22, 2026

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging
06:08

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

Published on: February 7, 2014

Determinants of brachial-ankle pulse wave velocity in a Japanese population: a cohort study

Satoko Mitani1, Masatoshi Fujita, Masako Shigeta

  • 1Unit for Liveable Cities, Kyoto University Graduate School of Medicine, Kyoto, Japan. mitani-satoko@hs.med.kyoto-u.ac.jp

Blood Pressure
|May 24, 2012
PubMed

Insights

Arterial stiffness, a predictor of coronary heart disease, was assessed using brachial-ankle pulse wave velocity (baPWV) and augmentation index (AI). The Framingham Risk Score correlated well with baPWV, suggesting its utility in assessing arterial stiffness.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Preventive Cardiology

Background:

  • Arterial stiffness is a significant predictor of coronary heart disease (CHD).
  • Assessing arterial stiffness aids in cardiovascular risk stratification.
  • Understanding the relationship between arterial stiffness markers and traditional risk factors is crucial for preventive strategies.

Purpose of the Study:

  • To evaluate the correlation between brachial-ankle pulse wave velocity (baPWV) and augmentation index (AI) with established risk factors for coronary heart disease (CHD).
  • To determine the applicability of the Framingham Risk Score (FRS) as an index of arterial stiffness in a healthy Japanese population.

Main Methods:

  • Cross-sectional study involving 528 healthy workers (mean age 47.9 years).
  • Measurements included brachial-ankle pulse wave velocity (baPWV) and augmentation index (AI).
  • Correlation and multivariate linear regression analyses were performed using Framingham Risk Score (FRS), body mass index, alcohol consumption, and AI P75.

Main Results:

  • The Framingham Risk Score (FRS) demonstrated a significant correlation with brachial-ankle pulse wave velocity (baPWV) (r = 0.53, p < 0.01).
  • Multivariate analysis identified FRS, body mass index, alcohol consumption, and AI P75 as significant correlates of baPWV.
  • Despite controlled blood pressure, individuals with hypertension treatment showed persistent arterial stiffness, while augmentation index (AI) was notably low.

Conclusions:

  • The Framingham Risk Score (FRS) is a valid index for assessing arterial stiffness in Japanese individuals.
  • Arterial stiffness is associated with multiple cardiovascular risk factors, including FRS, BMI, and alcohol consumption.
  • Further research is needed to understand the implications of low AI in treated hypertensive patients with residual arterial stiffness.

More Related Videos

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness05:51

Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness

Published on: May 3, 2018

Related Concept Videos

Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
Sites for measuring blood pressure01:21

Sites for measuring blood pressure

Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
Assessing Blood pressure in the Leg01:11

Assessing Blood pressure in the Leg

Proper measurement of leg blood pressure is a critical skill for healthcare providers, ensuring precise and reliable readings. When performed correctly, this procedure informs patient care and enhances the efficacy of interventions. The following text outlines step-by-step guidelines to measure blood pressure in the leg, providing clarity and ease of understanding for practitioners.
Preparation:
Assessment of radial pulse01:11

Assessment of radial pulse

Assessment of Radial Pulse
The radial pulse, located at the wrist, is often the preferred site for assessing peripheral pulse because of its accessibility and dependability. The process of determining the radial pulse involves several steps:
Assessment of apical radial pulse01:25

Assessment of apical radial pulse

Apical-Radial (A-R) Pulse Assessment
The A-R pulse assessment involves simultaneous evaluation of the apical and radial pulses. When the apical and radial pulse rates vary, this assessment helps identify a pulse deficit.
Pre-Procedural Preparation