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Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also called...
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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

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Related Experiment Video

Updated: May 22, 2026

Fabricating Degradable Thermoresponsive Hydrogels on Multiple Length Scales via Reactive Extrusion, Microfluidics, Self-assembly, and Electrospinning
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Stimuli-responsive supramolecular polymeric materials.

Xuzhou Yan1, Feng Wang, Bo Zheng

  • 1Department of Chemistry, Zhejiang University, Hangzhou 310027, PR China.

Chemical Society Reviews
|May 24, 2012
PubMed
Summary
This summary is machine-generated.

Supramolecular polymers utilize reversible noncovalent interactions for dynamic assembly. These adaptable materials offer unique properties like self-healing, making them promising for advanced applications.

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Last Updated: May 22, 2026

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Controlling the Size, Shape and Stability of Supramolecular Polymers in Water
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Controlling the Size, Shape and Stability of Supramolecular Polymers in Water

Published on: August 2, 2012

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Supramolecular Chemistry

Background:

  • Supramolecular materials are defined by reversible connections, enabling dynamic assembly and disassembly.
  • Their properties stem from the dynamic and reversible nature of noncovalent interactions.

Purpose of the Study:

  • To review recent advancements in supramolecular polymeric materials.
  • To highlight the fundamental role of noncovalent interactions in material responsiveness.

Main Methods:

  • Critical review of existing literature on supramolecular polymers.
  • Analysis of stimuli-responsive behaviors driven by noncovalent interactions.

Main Results:

  • Supramolecular polymers exhibit adaptable properties like degradability, shape-memory, and self-healing.
  • These materials respond to external stimuli due to their inherent noncovalent bonding.

Conclusions:

  • Supramolecular polymers represent a unique class of adaptable materials.
  • Noncovalent interactions are key to their responsiveness and potential applications.