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Updated: Jul 5, 2026

Computational Modeling of Retinal Neurons for Visual Prosthesis Research - Fundamental Approaches
Published on: June 21, 2022
Analysis of "integrate-to-threshold" neural coding schemes
Abstract:
Methods of analysis for some deterministic and stochastic variants of the integrate-to-threshold neural coding scheme are presented. Adaptation phenomena are modeled by means of feedforward and feedback adaptive threshold control. Simulations of sinusoidal and step responses reproduce satisfactorily the qualitative characteristics of adaptation as compared with physiological data. It is postulated that such adaptive threshold control may be accomplished by the release, or conformation change, of molecules involved in the control of excitable-channel dynamics.
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