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Related Concept Videos

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
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Updated: May 22, 2026

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
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A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

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[Calcified].

L Gerber1, A Gaspert, J A Bleisch

  • 1Klinik für Nephrologie, Universitätsspital Zürich, Germany.

Praxis
|May 24, 2012
PubMed
Summary
This summary is machine-generated.

Phosphate nephropathy, a kidney injury, can result from ingesting phosphate-containing purgatives like Colophos®. This case highlights risks in elderly women with pre-existing kidney issues, emphasizing the need for awareness.

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Last Updated: May 22, 2026

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Area of Science:

  • Nephrology
  • Toxicology
  • Gastroenterology

Background:

  • Phosphate nephropathy is a kidney disease often linked to the ingestion of phosphate-based purgatives.
  • Risk factors include advanced age, female sex, pre-existing kidney impairment, hypertension, and dehydration.

Observation:

  • A 73-year-old woman experienced acute kidney failure following bowel preparation for a colonoscopy.
  • Kidney biopsy revealed phosphate nephropathy, with Colophos®, a phosphate-containing purgative, identified as the causative agent.

Findings:

  • The patient's kidney function initially worsened post-exposure but gradually improved over several months.
  • Phosphate nephropathy can lead to irreversible tubulointerstitial damage and, in some cases, end-stage renal disease.

Implications:

  • This case underscores the importance of identifying phosphate-containing agents in acute kidney injury evaluations.
  • Awareness of risk factors is crucial for preventing phosphate nephropathy, particularly in vulnerable patient populations.
  • Minimizing exposure to oral phosphate purgatives in at-risk individuals is essential for kidney health preservation.