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Essential thrombocythaemia associated with priapism: a case report.
M A Durosinmi1, O A Badejo, B A Ayoade
1Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
East African Medical Journal
|August 1, 1990
Summary
Priapism, a prolonged erection, can complicate essential thrombocythaemia. This case highlights a Nigerian patient with thrombocythaemia experiencing priapism despite treatment, underscoring the condition
Area of Science:
- Hematology
- Urology
- Clinical Case Reports
Background:
- Essential thrombocythaemia is a myeloproliferative neoplasm characterized by elevated platelet counts.
- Priapism is a rare but serious complication that can occur in patients with myeloproliferative disorders.
- Understanding the interplay between thrombocythaemia and priapism is crucial for effective patient management.
Observation:
- A 45-year-old Nigerian male gardener presented with priapism.
- The patient exhibited significantly elevated platelet counts (1.2-1.6 x 10(12)/L), elevated leucocytes (23.4-30.6 x 10(9)/L), and borderline low haematocrit (0.25-0.33 L/L).
- Splenomegaly measuring 5cm was noted on examination.
Findings:
- The patient underwent bilateral cavernostomy for the management of priapism.
- Despite surgical intervention, the patient had not regained penile erection 3 to 2 months post-surgery.
- This case illustrates a challenging clinical scenario where priapism associated with essential thrombocythaemia proved refractory to standard treatment.
Implications:
- This case underscores the potential for severe urological complications in essential thrombocythaemia.
- It highlights the need for vigilant monitoring and potentially novel therapeutic strategies for priapism in this patient population.
- Further research into the pathophysiology and management of priapism in essential thrombocythaemia is warranted.