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Pathologic validation of clot length determined using thin section non-contrast CT.

Albert J Yoo¹, Thabele M Leslie-Mazwi, Christian H Riedel

¹Department of Radiology, Division of Interventional Neuroradiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA. ajyoo@partners.org

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|May 24, 2012

Summary

Thin section non-contrast CT (NCCT) accurately measures intracranial thrombus length in acute ischemic stroke. This measurement predicts vessel recanalization after thrombolytic therapy, aiding treatment decisions.

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Area of Science:

Neuroradiology
Neurointerventional Surgery
Stroke Imaging

Background:

Acute ischemic stroke management relies on accurate thrombus assessment.
Intracranial thrombus length is a predictor of treatment response.
Thin section non-contrast CT (NCCT) is a rapid imaging technique.

Observation:

A case of acute ischemic stroke with left middle cerebral artery occlusion is presented.
Pretreatment thin section NCCT was used to measure the intracranial thrombus length.
Pathological examination confirmed the clot length after endovascular therapy.

Findings:

The NCCT-measured clot length demonstrated high concordance with pathological findings.
This case supports the reliability of thin section NCCT for determining thrombus length.
Accurate clot length measurement is crucial for predicting recanalization after intravenous thrombolysis.

Implications:

Thin section NCCT can be reliably used to assess intracranial thrombus length in acute ischemic stroke.
Accurate clot length measurement may optimize patient selection for endovascular therapy.
This imaging approach can improve prediction of vessel recanalization and clinical outcomes.