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Related Concept Videos

Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

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Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
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Kaolin-activated thromboelastography in echocardiographically normal cats.

Daniel J Hall1, John E Rush, Armelle M deLaforcade

  • 1Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA. dhall@scvetspecialists.com

American Journal of Veterinary Research
|May 25, 2012
PubMed
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Kaolin-activated thromboelastography (TEG) provides reliable hemostasis values in healthy cats. Sedation minimally impacts TEG results, suggesting its utility in feline veterinary diagnostics.

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Area of Science:

  • Veterinary diagnostics
  • Hemostasis analysis
  • Feline medicine

Background:

  • Thromboelastography (TEG) is a valuable tool for assessing hemostasis.
  • Establishing reference values is crucial for accurate interpretation in specific species.
  • Echocardiographic assessment aids in identifying cardiac health in cats.

Purpose of the Study:

  • To establish reference values for kaolin-activated TEG in echocardiographically normal cats.
  • To assess the reliability and intra-assay variability of the TEG test in this population.
  • To investigate the potential impact of sedation on TEG parameters.

Main Methods:

  • Echocardiographic examination of 30 healthy cats by a board-certified cardiologist.
  • Blood sample collection for kaolin-activated TEG analysis.
  • Analysis of TEG variables, PCV, total solids, platelet count, aPTT, PT, fibrinogen, and antithrombin levels.

Main Results:

  • Kaolin-activated TEG demonstrated low intra-assay variability (<5%) for all tested variables.
  • Mean values obtained: reaction time (4.3 min), clotting time (1.6 min), α angle (66.5°), and maximum amplitude (56.4 mm).
  • Sedation resulted in a shorter clotting time and greater α angle, with no significant changes in reaction time or maximum amplitude.

Conclusions:

  • Kaolin-activated TEG is a reliable diagnostic test in echocardiographically normal cats.
  • Sedation has a minor, likely clinically insignificant, effect on certain TEG parameters.
  • Further research is needed to determine the effect of subclinical cardiomyopathy on feline TEG values.