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Updated: May 22, 2026
04:44
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[History of systemic sclerosis]
Hugo Armando Laborde1, Pablo Young
1Servicio de Reumatología, Hospital Británico de Buenos Aires, Buenos Aires, Argentina.
Gaceta Medica De Mexico
|May 25, 2012
Summary
Systemic sclerosis, or scleroderma, is a connective tissue disease causing fibrosis. This review highlights historical medical contributions to understanding and treating this complex condition.
Area of Science:
- Rheumatology and Immunology
- Pathology
- Medical History
Context:
- Systemic sclerosis (Scleroderma) is a generalized connective tissue disease with unknown etiology.
- Characterized by fibrosis and degenerative changes affecting skin, joints, vasculature, muscle, and internal organs (GI tract, lungs, heart, kidneys).
- Clinical recognition of scleroderma has evolved from ancient descriptions to precise diagnoses in the late 19th century.
Purpose:
- To review the historical progression of understanding Systemic Sclerosis (Scleroderma).
- To acknowledge the key physicians and their contributions to advancing the diagnosis and treatment of scleroderma.
- To provide historical context for current clinic-serologic classifications and therapeutic strategies.
Summary:
- Systemic sclerosis is a multisystem fibrotic disease of unknown cause.
- Historical medical records document cutaneous alterations suggestive of scleroderma since antiquity.
- Advances in pathogenesis knowledge and classification in the 20th century enabled improved diagnosis and treatment.
Impact:
- Enhanced understanding of scleroderma's historical diagnostic and therapeutic milestones.
- Recognition of the cumulative efforts of medical professionals in advancing scleroderma care.
- Provides a foundation for appreciating current knowledge and future research directions in rheumatology.
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