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Risk factors for spinal anesthesia in preterm infants undergoing inguinal hernia repair
Ze'ev Shenkman1, Ilan Erez, Enrique Freud
1Department of Anesthesia, Sheba Medical Center, Tel Hashomer, Israel.
Insights
Spinal anesthesia is safe for preterm infants undergoing hernia repair, with low complication rates. However, conditions like bronchopulmonary dysplasia increase risks for adverse outcomes.
Area of Science:
- Pediatric Anesthesiology
- Neonatal Surgery
Background:
- Spinal anesthesia is increasingly used for neonatal surgery.
- Preterm infants may have unique risks associated with anesthesia.
Purpose of the Study:
- To determine the incidence of perioperative adverse effects of spinal anesthesia in preterm infants undergoing inguinal hernia repair.
- To identify risk factors for unfavorable outcomes and evaluate feeding and discharge times.
Main Methods:
- Prospective data collection from preterm and former preterm infants undergoing inguinal hernia repair with spinal anesthesia.
- Analysis of intraoperative and postoperative complications, and time to oral feeding and discharge.
Main Results:
- Six (4.2%) intraoperative complications (apnea, bradycardia, hypoxemia) and 15 (10.4%) postoperative complications were observed.
- Bronchopulmonary dysplasia (OR=3.2) and periventricular leukomalacia (OR=2.8) were significant predictors of unfavorable outcomes.
Conclusions:
- Spinal anesthesia is safe and effective for inguinal hernia repair in preterm infants, facilitating early feeding and short hospital stays.
- Bronchopulmonary dysplasia and periventricular leukomalacia are risk factors for adverse outcomes in this population.
Objectives:
To investigate the risk factors and incidence of perioperative adverse effects from unsupplemented spinal anesthesia in preterm infants. Times to resumption of oral feeding and to home discharge were also evaluated.
Methods:
Perioperative data were collected prospectively for all preterm and former preterm infants who underwent inguinal hernia repair with spinal anesthesia at a tertiary medical center.
Results:
The study group consisted of 144 infants with a median gestational age of 30 weeks, postmenstrual age of 37 weeks, birth weight of 1,420 g, and weight at surgery of 2,140 g. Overall, six (4.2%) infants had intraoperative complications, which included apnea (2/1.4%), bradycardia (2/1.4%), and hypoxemia (4/2.8%). Postoperative complications occurred in 15 (10.4%) infants, mainly hypoxemia (3/2.1%), bradycardia (8/5.5%), and apnea (6/4.1%). Predictive factors of an unfavorable outcome (apnea, resumption of oral feeding > 6 h postoperatively, or discharge > 30 h postoperatively) were bronchopulmonary dysplasia (odds ratio [OR] = 3.2, 95% confidence interval [95%CI] 2.8-5.3; p = 0.01) and periventricular leukomalacia (OR = 2.8, 95%CI 2.1-4.9; p = 0.03).
Conclusions:
Spinal anesthesia is safe and effective for inguinal hernia repair in preterm infants, with early resumption of oral feeding and short hospitalization. Bronchopulmonary dysplasia and periventricular leukomalacia may pose risks for an unfavorable outcome.
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