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Updated: May 22, 2026
08:16
High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
Published on: March 16, 2022
Vascular laboratory for critical limb ischaemia
M Venermo1, P Vikatmaa, H Terasaki
1Department of Vascular Surgery, Helsinki University Central Hospital, Helsinki, Finland. maarit.vernermo@hus.fi
Summary
This review examines past and present vascular assessment methods for critical limb ischaemia, integrating Finnish and Japanese clinical experiences. It highlights evolving diagnostic strategies and their impact on patient outcomes in limb salvage.
Area of Science:
- Vascular Surgery
- Vascular Medicine
- Ischaemia Research
Background:
- Critical limb ischaemia (CLI) poses a significant challenge in vascular medicine, necessitating accurate diagnostic tools for timely intervention.
- Historical approaches to vascular assessment for CLI have evolved considerably, influenced by technological advancements and clinical experience.
Purpose of the Study:
- To provide a comprehensive narrative review of vascular assessment techniques for CLI.
- To compare and contrast past and present methodologies, drawing upon Finnish and Japanese healthcare system experiences.
- To identify key developments and best practices in the diagnosis and management of CLI.
Main Methods:
- A narrative review methodology was employed, synthesizing existing literature and clinical insights.
- Comparative analysis of vascular assessment strategies used in Finland and Japan.
- Focus on diagnostic modalities and their historical progression.
Main Results:
- Significant advancements in non-invasive and invasive vascular imaging have transformed CLI assessment.
- Integration of diverse clinical experiences from Finland and Japan offers unique perspectives on diagnostic efficacy.
- Current assessment protocols emphasize a multi-modal approach for comprehensive evaluation.
Conclusions:
- Accurate vascular assessment is paramount for effective CLI management and limb salvage.
- Continuous evolution of diagnostic tools and techniques improves patient outcomes.
- International collaboration and experience sharing, exemplified by Finnish and Japanese contributions, are vital for advancing CLI care.
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