Blood donation and risk of post-transfusion hepatitis

A survey was conducted among 300 blood donors of urban and rural population (the Sunderbans) and paid donors to evaluate the nutritional status, serum proteins, immunoglobulin and alanine aminotransferase (ALT) on the persistence of carrier state for post-transfusion hepatitis (PTH). Paid donors showed lowering of serum albumin and elevation of immunoglobulin and ALT. Nutritional and immunoglobulin profiles of rural donors of the Sunderbans, differed from those of voluntary donors of urban area. In the presence of subclinical hepatitis, ALT measurement alone is not a reliable guide for identification of individual carriers.