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Differences between multisite postmortem ethanol concentrations as related to agonal events.

J V Marraccini1, T Carroll, S Grant

  • 1Office of the Medical Examiner, Palm Beach County, FL.

Journal of Forensic Sciences
|November 1, 1990
PubMed
Summary
This summary is machine-generated.

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Postmortem ethanol analysis requires careful interpretation. Agonal aspiration of vomitus can elevate aortic ethanol levels, impacting forensic toxicology results.

Area of Science:

  • Forensic Toxicology
  • Postmortem Analysis
  • Ethanol Pharmacokinetics

Background:

  • Accurate postmortem ethanol concentration determination is crucial for forensic investigations.
  • Variability in blood ethanol concentrations (BEC) at different sampling sites can complicate interpretation.
  • Understanding factors influencing postmortem ethanol distribution is essential.

Observation:

  • Blood samples were collected from the right atrium, ascending aorta, and inferior vena cava in 307 autopsies with a minimum BEC of 0.05% w/v.
  • Vitreous humor and gastric fluid were also analyzed.
  • Premortem, agonal, and postmortem events were reviewed to explain BEC discrepancies.

Findings:

  • Agonal aspiration of vomitus containing at least 0.80% w/v ethanol was associated with increased aortic ethanol concentrations.

Related Experiment Videos

  • Differences in BEC between sampling sites were observed and analyzed in relation to patient events.

    • Implications:

    • Valid interpretation of postmortem ethanol concentrations necessitates consideration of potential ethanol entry into the pulmonary venous circulation via the respiratory system.
    • Findings highlight the importance of considering aspiration events in forensic ethanol analysis.
    • This study contributes to refining methodologies for postmortem toxicology assessments.