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Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus (MRSA) in Rat

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Bacillus cereus endocarditis in native aortic valve.

H A Ngow¹, W M N Wan Khairina

¹Internal Medicine Department, Kulliyyah of Medicine, International Islamic University Malaysia, P.O. Box 141, Kuantan, Pahang Darul Makmur, Malaysia. harrisngow@gmail.com

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy

|May 26, 2012

Summary

Bacillus cereus endocarditis is a rare infection, particularly affecting native valves. This case highlights a unique instance in a former intravenous drug user with severe aortic regurgitation.

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Area of Science:

Infectious Diseases
Cardiology
Microbiology

Background:

Bacillus cereus endocarditis is infrequently documented.
It is often associated with immunocompromised states, intravenous drug use, or prosthetic cardiac devices.
Native valve involvement is exceptionally rare.

Observation:

A 31-year-old male with a history of intravenous drug use and previous staphylococcal endocarditis presented with heart failure symptoms.
Echocardiography revealed severe aortic regurgitation and a vegetation on the aortic valve's right coronary cusp.
Blood cultures confirmed the presence of Bacillus cereus.

Findings:

The study reports a rare case of native aortic valve endocarditis caused by Bacillus cereus.
This presentation occurred in a patient with significant risk factors for infective endocarditis.

Implications:

This case expands the known spectrum of Bacillus cereus as a causative agent of endocarditis.
It underscores the importance of considering Bacillus cereus in cases of endocarditis, even in native valves.
Clinicians should maintain a high index of suspicion in at-risk populations.