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Updated: May 22, 2026

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

Published on: March 30, 2014

Enhancing HIV medication adherence in India.

Deborah Jones¹, Aman Sharma, Mahendra Kumar

¹Miller School of Medicine, University of Miami, Miami, FL, USA.

Journal of the International Association of Providers of AIDS Care

|May 26, 2012

Summary

Early group interventions significantly improve antiretroviral therapy (ART) adherence in new patients. This pilot study highlights the importance of timely support for establishing long-term medication adherence behaviors.

Keywords:

India adherence assessment behavior intervention

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Published on: April 9, 2014

Area of Science:

Clinical Medicine
Public Health
Pharmacology

Background:

Pilot study assessing an intervention to improve adherence in individuals starting antiretroviral therapy (ART).
High adherence is crucial for effective HIV management and preventing drug resistance.

Purpose of the Study:

To evaluate the effectiveness of a group intervention versus individual enhanced standard care for enhancing ART adherence.
To determine if early intervention impacts long-term adherence behaviors.

Main Methods:

80 participants recruited from a hospital clinic in Chandigarh, India.
Randomized controlled trial with a 3-month group intervention or individual care, followed by crossover and 6-month assessment.
Adherence measured via prescription refill, pill count, and self-report.

Main Results:

At baseline, over 50% of participants exhibited nonadherence by pill count.
The group intervention condition showed significantly improved adherence compared to the individual condition from postintervention to long-term follow-up (χ(2) = 5.67, P = .02).

Conclusions:

Early interventions providing information and social support are effective in establishing long-term adherence behaviors.
Group-based support may be a valuable strategy for improving ART adherence in new patients.