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Updated: May 22, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
X-linked ichthyosis along with epidermolysis bullosa
Shambulingappa Pallagatti1, Soheyl Sheikh, Anupreet Kaur
1Department of Oral Medicine and Radiology, M.M. College of Dental Sciences and Research, Mullana, Ambala, Haryana, India.
Abstract:
Ichthyoses are a heterogenous group of hereditary keratinization disorders that share in common the accumulation & shedding of large amounts of hyperkeratotic epidermis. Early reports of ichthyosis in the Indian and Chinese literature date back to several hundred years. X-linked recessive ichthyosis (XLI) is a common disorder of keratinization and affects males who inherit an X-chromosome having a steroid sulphatase genetic mutation. In the present communication we report a case of XLI and dystrophic epidermolysis bullosa in the same patient. To the best of our knowledge it has been reported only once before.
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