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Published on: September 18, 2013
The binding of radioiodinated thrombin to rat promegakaryoblasts
1Department of Medicine, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick 08903.
Journal of Receptor Research
|January 1, 1990
Abstract:
Rat promegakaryoblasts have recently been shown to possess a number of properties of mature platelets. We have studied the binding of 125I-thrombin to these cells grown in culture. The binding was found to be saturable, specific, reversible, and of high affinity. Such cell lines may be useful models for the study of platelet-agonist interactions.

