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[Changes in the liver weight in the elderly].

M Katayama1, K Yamazumi, K Kino

  • 1Tokyo Metropolitan Geriatric Hospital.

Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
|September 1, 1990
PubMed
Summary
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Aging decreases liver weight and its body weight ratio in the elderly. Obesity further influences these changes, with obese individuals showing increased liver weight but decreased liver-to-body weight ratios with age.

Area of Science:

  • Gerontology
  • Hepatology
  • Human Anatomy

Context:

  • Liver weight changes with age and obesity in the elderly population.
  • Autopsy data from 582 elderly individuals (291 male, 291 female) were analyzed.
  • Cases with pathological findings affecting liver weight were excluded.

Purpose:

  • To investigate the impact of aging on liver weight and its proportion to body weight in elderly individuals.
  • To examine how obesity modifies the age-related changes in liver weight.

Summary:

  • Liver weight and its ratio to body weight decline with advancing age in the elderly.
  • Obesity leads to increased liver weight but a decreased liver-to-body weight ratio.
  • These age-related trends persist across different degrees of obesity and show sex-specific differences.

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Impact:

  • Provides crucial data for understanding age-related physiological changes in the liver.
  • Informs clinical assessments and interpretations of liver parameters in elderly patients.
  • Highlights the complex interplay between aging, obesity, and liver mass.