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Published on: August 25, 2014
Patterns of functioning and predictive factors in children born moderately preterm or at term
Renata Cserjesi1, Koenraad Nja VAN Braeckel, Marieke Timmerman
1Department of Clinical and Developmental Neuropsychology, University of Groningen, Groningen, the Netherlands. r.cserjesi@rug.nl
Insights
Children born moderately preterm (MPT) show slightly affected neurodevelopmental functioning at school age. Poorer performance is linked to below-average abilities, particularly in children with low parental education.
Area of Science:
- Neurodevelopmental Pediatrics
- Developmental Psychology
- Child Health
Background:
- Children born moderately preterm (MPT) may experience neurodevelopmental challenges.
- Identifying distinct functioning subgroups and predictive factors is crucial for targeted interventions.
Purpose of the Study:
- To identify subgroups of children born MPT and at term with varying functional levels.
- To determine perinatal and demographic predictors of subgroup membership.
Main Methods:
- Latent class analyses were conducted on 378 seven-year-old children (248 MPT, 130 term).
- Measures included intelligence, memory, attention, executive function, and motor skills.
- χ(2) automatic interaction detection identified subgroup-predictor associations.
Main Results:
- Four distinct performance subgroups were identified.
- Parental education was the sole significant predictor of subgroup assignment (p < 0.01).
- The lowest-performing subgroup exhibited irregular patterns, with attentional deficits but relative strengths in intelligence and memory.
Conclusions:
- Poorer performance in MPT children reflects a higher proportion of below-average functioning, not an extremely impaired subgroup.
- MPT birth has a slight impact on neurodevelopmental functioning at early school age.
- Low parental education exacerbates the effects of MPT birth on neurodevelopment.
Aim:
The aim of this study was to identify subgroups of children born moderately preterm (MPT) and term with distinctive levels and patterns of functioning, and the perinatal and demographic factors that predict subgroup membership.
Method:
A total of 378 children aged 7 years, 248 MPT (138 males, 110 females; gestational age 32-36 wks) and a comparison group of 130 children born at term (58 males, 72 females; gestational age 38-41 wks), were selected from a community-based cohort study. Latent class analyses were performed on measures of intelligence, verbal memory, attention, executive functioning, and visuomotor and motor skills. χ(2) automatic interaction detection analyses were performed to detect associations between the subgroups and predictors.
Results:
Four subgroups differing in levels of performance were identified, with parental education being the only statistically significant determinant of subgroup assignment (p < 0.01). The subgroup that performed the most poorly showed an irregular pattern of performance, with specific weakness in attentional skill and relative strength in intelligence and verbal memory. Parental education predicted classification probability in the preterm group (p = 0.04) but not in the term group (p = 0.15).
Interpretation:
Our results show that the poorer performance of children born MPT reflects a higher proportion of children with below average performance rather than a subgroup with extremely poor performance. They indicate that MPT birth affects neurodevelopmental functioning at early school age only slightly, with effects being largest in such children with low parental education.
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