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Updated: May 22, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Purpuric drug eruption and alopecia induced by erlotinib
Abstract:
We herein report a case of diffuse alopecia with pustules on the scalp and purpuric lesions on the lower legs in a Japanese man after treatment with erlotinib. This is a unique case in which rare skin eruptions simultaneously occurred. We discuss herein a combination of skin eruptions as an adverse reaction of epidermal growth factor-receptor (EGF-R) tyrosine kinase inhibitor. It is indispensable to be aware of rare skin reactions when applying molecular targeting therapies.
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