[Acute neutrophilic febrile dermatosis (Sweet syndrome) associated with melanoma]

A 45-years-old woman affected of Acute febrile neutrophilic syndrome is presented, with no reliable etiology. In a rutinary control, a pigmented ledion of one year of evolution was observed and a surgical excision was performed, with histological diagnosis of spreading superficial melanoma. In the next weeks of post-operatory, the Sweet's syndrome was decreased, disappearing completely two months later. No recurrences of Sweet's syndrome or malignant melanoma were observed after two years of follow-up. Association between Sweet's syndrome and neoplasias, in particular solid tumors, is commented, and the literature is reviewed.