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Bovine trophoblastic cell differentiation and binucleation involves enhanced endogenous retrovirus element expression

Katsuo Koshi1, Yasunori Suzuki, Yuki Nakaya

  • 1Laboratory of Veterinary Physiology, Department of Veterinary Medicine, Faculty of Agriculture, Iwate University, 3-18-8 Ueda, Morioka, Iwate 020-8550, Japan.

Reproductive Biology and Endocrinology : RB&E
|May 29, 2012
PubMed
Summary

Bovine endogenous retrovirus (ERV) envelope genes, specifically bERVE-A and BERV-K1 env, are involved in bovine trophoblastic cell binucleation. Their expression increases during the formation of binucleate cells (BNCs) in vitro.

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