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[Chemonucleolysis with chymopapain in lumbar disk hernia. Randomized comparative study with operated patients]
1Neurochirurgische Klinik, Kantonsspital Basel.
Neurochirurgia
|September 1, 1990
Summary
Chemonucleolysis with chymopapain offers lasting success for 88% of patients, comparable to surgery. Proper patient selection and technique can avoid complications and surgical intervention.
Area of Science:
- Orthopedics
- Minimally Invasive Procedures
Background:
- Chemonucleolysis with chymopapain is a less invasive treatment option for certain spinal conditions.
- This method has faced criticism, necessitating objective evaluation.
Purpose of the Study:
- To compare the efficacy and outcomes of chemonucleolysis with chymopapain versus surgical treatment.
- To assess the safety and success rates of chemonucleolysis in a randomized study.
Main Methods:
- A randomized comparison study involving 69 patients.
- One group (41 patients) underwent surgery, while the other (25 patients) received chemonucleolysis with chymopapain.
Main Results:
- Chemonucleolysis with chymopapain demonstrated lasting success in 88% of patients.
- Surgical treatment resulted in good condition for nearly 90% of patients.
- Complication rates were evaluated in relation to patient selection and procedural technique.
Conclusions:
- Chemonucleolysis with chymopapain is a viable alternative to surgery when performed with appropriate patient selection and technique.
- The procedure can potentially spare patients from surgical intervention and associated risks.
- This study supports the continued use of chemonucleolysis with chymopapain.