Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Joint hypermobility in keratoconus.

E G Woodward1, M T Morris

  • 1Department of Optometry & Visual Science, City University, London, UK.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|October 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of age on the light scattering characteristics of the eye.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·1998
Same author

Use of contact lenses by firefighters: Part 2. Clinical evaluation.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·1997
Same author

Use of contact lenses by firefighters. Part 1: Questionnaire data.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·1997
Same author

A new computer assisted objective method for quantifying vascular changes of the bulbar conjunctivae.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·1996
Same author

Optimal photographic imaging of the bulbar conjunctival vasculature.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·1996
Same author

Screening for diabetic retinopathy.

BMJ (Clinical research ed.)·1996
Same journal

Mesopic Illumination in Natural Environments: Implications for Myopia Research.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Axial Length Growth Reference Curves and LMS Parameters for Japanese Children and Adolescents Aged 4-20 Years: The TMM BirThree Cohort Study.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Effect of Switching Myopia Control Strategies on Axial Elongation in Children with Poor Response to Highly Aspherical Lenslet Therapy.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Quantifying the Role of Longitudinal Chromatic Aberration and Age in Night Vision Disturbances.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Impaired Rod-Mediated Vision is the Functional Hallmark of Ageing and Early and Intermediate Age-Related Macular Degeneration.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
Same journal

Analytical Performance, Spatial Dynamics and Clinically Meaningful Change Thresholds for Automated Non-invasive Tear Film Assessment Using the Oculus Keratograph 5M.

Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)·2026
See all related articles

Patients with keratoconus exhibit increased joint hypermobility, particularly in the metacarpo-phalyngeal and wrist joints. This suggests keratoconus may stem from mild, localized connective tissue disorders affecting collagen metabolism.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Genetics

Background:

  • Keratoconus is frequently associated with connective tissue disorders like Ehlers-Danlos syndrome.
  • These associations suggest a potential link between keratoconus and localized collagen metabolism dysfunction.

Purpose of the Study:

  • To investigate the incidence of joint hypermobility in keratoconus patients.
  • To compare joint hypermobility in keratoconus patients with a matched control group.

Main Methods:

  • Eighty-four keratoconus patients and a matched control group were assessed.
  • The Beighton modification of the Carter and Wilkinson scoring system was used to evaluate joint hypermobility.

Main Results:

  • No significant differences in trunk or knee joint hypermobility were observed between groups.

Related Experiment Videos

  • Statistically significant hypermobility was found in the metacarpo-phalyngeal and wrist joints of keratoconus patients.
  • Keratoconus patients were five times more likely to exhibit hypermobility in these specific joints.

    • Conclusions:

    • The findings support the hypothesis that keratoconus represents a localized manifestation of a mild connective tissue disorder.
    • Increased hypermobility in specific joints may serve as a clinical indicator associated with keratoconus.