Related Experiment Video
Updated: May 22, 2026

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
Published on: February 23, 2014
Pneumonia hospitalization in Brazil from 2003 to 2007
Eitan Namaan Berezin1, José Cássio de Moraes, Ting Hong
1Faculdade de Ciências Médicas da Santa Casa de São Paulo, Av Roberto Lorenz 482, 05611-050, São Paulo, SP, Brazil. berezin@terra.com.br
Objectives:
In emerging countries, pneumonia is a leading cause of hospitalization and death, particularly among the youngest and oldest. This retrospective study aimed to quantify the incidence of hospitalization due to all-cause pneumonia (HDTP) and in-hospital case fatality rates (CFRs) in all age groups, in five administrative regions of Brazil.
Methods:
The International Classification of Diseases Tenth Revision coding for pneumonia (J12-J18) and an interactive web-based database of individuals covered by the Unified Health System in Brazil who were hospitalized from 2003 to 2007, were used to identify cases. In-hospital CFRs were the percentage of hospitalized cases that died.
Results:
The overall HDTP incidence per 100,000 people of all ages decreased from 451 in 2003 to 388 in 2007. When categorized by age group, the HDTP incidence was lowest for those aged 5-49 years, and highest in children aged ≤4 years and adults aged ≥50 years. The in-hospital CFR increased from 2.89% in 2003 to 4.02% in 2007. Regional differences in HDTP incidence rates and in-hospital CFR were observed from 2003 to 2007.
Conclusions:
As expected, the highest HDTP rates were observed in the very young and the elderly. Regional differences in hospitalization incidence rates and in-hospital CFRs were observed.
Related Concept Videos
Pneumonia I: Introduction
Pneumonia I: Introduction
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia IV: Management
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Pneumonia III: Complications and Assessment
Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed.
Pneumonia II: Pathophysiology

