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Updated: May 22, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
[Biological fragility syndrome in the elderly: systematic review]
Sheilla Tribess1, Ricardo Jacó de Oliveira
1Instituto de Ciências da Saúde, Universidade Federal do Triângulo Mineiro, Uberaba, MG, Brazil. sheilla@ef.uftm.edu.br
Objective:
The aim of this study was to identify the prevalence and assessment strategies of Biological Fragility Syndrome in the Elderly.
Methods:
For the development of this study was it was done a search in electronic databases (Medline/PubMed) and the reference lists of articles identified using the following key words/terms in English: "frailty" and `frail" in conjunction with the terms "elderly", "aging" and "prevalence". These terms/descriptors were combined using the logical operators available in search engines. The initial electronic search resulted in 1 865 manuscripts. The process of analysis of the studies involved reading titles, abstracts and full texts. After all these phases, 35 manuscripts met the inclusion criteria of the review.
Results:
The results indicated that women, with rage from 7.3 % to 21.6 %, are frailer than men, with percentages ranging from 4 % to 19.2 %.
Conclusions:
Differences in prevalence rates of prefrailty and frailty should be minimized, with stimulus for standardization for the evaluation of human frailty.
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