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Mimicking and Measuring Occlusal Erosive Tooth Wear with the "Rub&Roll" and Non-contact Profilometry
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Severe tooth wear in Prader-Willi syndrome. A case-control study

Ronnaug Saeves1, Ivar Espelid, Kari Storhaug

  • 1TAKO-centre, Lovisenberg Diakonale Hospital, Lovisenberggt 17, 0440 Oslo, Norway. Ronnaug.Saeves@tako.no

BMC Oral Health
|May 30, 2012
PubMed

Insights

Individuals with Prader-Willi syndrome (PWS) experience severe tooth wear due to erosion and attrition. This highlights a significant need for dental rehabilitation in affected young adults.

Area of Science:

  • Genetics
  • Dentistry
  • Endocrinology

Background:

  • Prader-Willi syndrome (PWS) is a rare genetic disorder with multisystemic effects, including oral abnormalities.
  • Individuals with PWS often exhibit severe hypotonia, endocrine issues, hyperphagia, obesity, and cognitive impairments.

Purpose of the Study:

  • To investigate the prevalence of tooth wear in individuals with Prader-Willi syndrome.
  • To identify potential risk factors associated with tooth wear in the PWS population.

Main Methods:

  • A case-control study involving 49 individuals with PWS (aged 6-40) and an age/sex-matched control group.
  • Tooth wear assessed using the Visual Erosion Dental Examination (VEDE) and individual tooth wear index (IA) from dental casts, photographs, and clinical evaluation.
  • Whole saliva collection and analysis.

Main Results:

  • Significantly higher tooth wear (VEDE and IA scores) in the PWS group compared to controls (p < 0.001).
  • Tooth wear in PWS correlated with age, reduced saliva secretion, and tooth grinding.
  • Multivariate analysis confirmed PWS, age, and tooth grinding as significant predictors of tooth wear.

Conclusions:

  • Tooth wear, encompassing both erosion and attrition, is a critical issue in Prader-Willi syndrome.
  • Young adults with PWS demonstrate a substantial requirement for prosthodontic rehabilitation due to severe tooth wear.
Abstract

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