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Inferior Vena Cava collapsibility and heart failure signs and symptoms: new insights about possible links
Renato De Vecchis1, Antonio Ciccarelli, Carmelina Ariano
1Cardiology Unit, Presidio Sanitario Intermedio Elena d Aosta. r.de.vecchis@alice.it
Insights
In chronic heart failure, a low inferior vena cava collapsibility index (IVCCI) did not reliably predict congestion. However, IVCCI values ≤ 15% were consistently linked to decompensated heart failure signs.
Area of Science:
- Cardiology
- Critical Care Medicine
- Medical Imaging
Background:
- Ultrasound measurement of inferior vena cava collapsibility index (IVCCI) is explored for assessing hemodynamic congestion in chronic heart failure (CHF) patients.
- Accurate assessment of congestion is crucial for managing CHF and preventing adverse outcomes.
Purpose of the Study:
- To correlate physical examination findings with IVCCI measurements in CHF patients.
- To determine if baseline IVCCI values can predict persistent or worsening congestion after optimized oral therapy.
Main Methods:
- Retrospective cohort study of 54 CHF patients (NYHA class III).
- Patients categorized into three groups based on baseline IVCCI: ≤ 15%, 16-40%, and >40%.
- Clinical congestion criteria compared across groups; Cox multivariate analysis used.
Main Results:
- Jugular venous distension and rales were multivariate predictors of high congestion score.
- A baseline IVCCI ≤ 15% was always associated with high congestion at follow-up.
- However, IVCCI ≤ 15% did not reliably predict high congestion at the second visit.
Conclusions:
- Low IVCCI values (≤ 15%) do not reliably predict high congestion scores in CHF patients.
- Despite this, IVCCI ≤ 15% was consistently associated with signs of both right and left-sided CHF decompensation.
Background:
In chronic heart failure patients (CHF), ultrasound measurement of inferior vena cava collapsibility index (IVCCI) has been proposed to yield careful assessment and grading of the hemodynamic congestion.
Objective:
The purpose of this study was to correlate the findings of physical examination with IVCCI in CHF patients.
Methods:
According to a retrospective cohort design, we analyzed 54 CHF patients with right or biventricular CHF, belonging to III NYHA class. We planned to determine whether any basal IVCCI range would be able to predict persistent or worsening clinical congestion found at the end of subsequent follow up (i.e. after 1-2 months of oral optimized therapy). For this purpose, the patients were subdivided by three groups according to the basal IVCCI value: ≤ 15% (13 pts), 16 - 40% (21 pts) and > 40% (20 pts).Several clinical criteria of congestion were compared across the three groups and subsequently entered in the Cox multivariate model.
Results:
Multivariate predictors of high congestion score were jugular venous distension (HR: 13,38 95% C.I.: 2,13 - 84 p = 0,0059) and rales (HR: 11 95% C.I : 1,45 - 83,8 p = 0,0213). IVCCI ≤ 15% was always associated with high congestion score at the second visit; but IVCCI ≤ 15% failed to predict high congestion score at the second visit.
Conclusion:
In CHF setting, low IVCCI did not reliably predict high congestion score. Nevertheless, the cluster with IVCCI ≤ 15% was always found associated with signs and symptoms from both right and left-sided decompensated CHF.
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