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Updated: May 21, 2026

In vitro Synthesis of Native, Fibrous Long Spacing and Segmental Long Spacing Collagen
Published on: September 20, 2012
[Characteristics of collagen's material bifidogenic properties]
Abstract:
It is still essential to search for new, available food ingredients with bifidogenic effect, to study their safety, efficacy and production effectiveness upon the creation of functional foods. The review considers protein products such as collagens and their hydrolyzates, which are used in culture mediums as growth factor. They are treated, besides carbohydrate prebiotics, as potential bifidogenic nutrients. Collagen hydralyzates contain all amino acids, required for bifidobacteria growth. That is why it is considered essential to provide control over its biosafety. However, recyclable materials of animal origin are included into a list of Specific Risk Materials of prion disease agents transmitting. Collagen hydralyzates are preserved up to distal intestine parts. This fact approximates their qualities to oligosaccharids' type of prebiotic food fibers, related to the lack of absorption and hydrolytic stability. The additional study of mechanisms of bifidobacteria's forcing is required. It can be made at the expense of the modification of the albuminous cell metabolism during the collagen hydralyzats' unilization.
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