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In vivo Imaging of Optic Nerve Fiber Integrity by Contrast-Enhanced MRI in Mice
Published on: July 22, 2014
[Effectiveness of magnetotherapy in optic nerve atrophy. A preliminary study]
Vestnik Oftalmologii
|September 1, 1990
Summary
Magnetotherapy improved vision acuity and ocular hemodynamics in patients with optic nerve atrophy. This treatment stimulated retinal cells and reduced vision pathway conduction time, with maximal effects after 10 sessions.
Area of Science:
- Ophthalmology
- Biophysics
- Medical Technology
Background:
- Optic nerve atrophy significantly impairs visual functions.
- Current treatments for optic nerve atrophy have limited efficacy.
- Understanding novel therapeutic approaches is crucial for visual rehabilitation.
Purpose of the Study:
- To evaluate the efficacy of low-frequency magnetotherapy for optic nerve atrophy.
- To assess magnetotherapy's impact on visual acuity, visual field, and retinal function.
- To investigate the effects on the conductive vision system and intraocular circulation.
Main Methods:
- 88 patients (160 eyes) with optic nerve atrophy participated.
- Treatment involved a Soviet Polyus-1 apparatus with ~10 mT magnetic induction.
- Patients received 7-10 minute exposures over 10-15 sessions per course.
Main Results:
- Vision acuity improved in 50% of patients with initial low acuity (<0.04 diopters).
- The number of patients with 0.2 diopters vision acuity increased from 46 to 75.
- Magnetotherapy enhanced ocular hemodynamics, reduced visual pathway conduction time, and stimulated retinal ganglion cells.
Conclusions:
- Low-frequency magnetotherapy is a promising treatment for optic nerve atrophy.
- The therapy positively influences key visual parameters and ocular circulation.
- Maximal therapeutic effects were observed after 10 sessions, with stabilization after repeated courses.

