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Eosinophilic granulocytic sarcoma in a pig.
Juliana S Brum1, Ricardo B Lucena, Tessie B Martins
1Departamento de Patologia, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.
Summary
A rare eosinophilic granulocytic sarcoma was found in a pig, presenting as green masses in bones and organs. This veterinary case highlights the importance of thorough diagnostics for unusual neoplastic conditions.
Area of Science:
- Veterinary Pathology
- Oncology
- Animal Science
Background:
- Granulocytic sarcoma is a rare tumor of myeloid lineage.
- Eosinophilic differentiation in granulocytic sarcoma is exceptionally uncommon.
- This case involves a 5-year-old female pig presented for slaughter.
Observation:
- Gross examination revealed green masses in bones, skeletal muscles, lymph nodes, and kidneys.
- Cytology showed myelocytes with some exhibiting eosinophilic granularity.
- Histology confirmed neoplastic cells obliterating bone marrow architecture.
Findings:
- Neoplastic cells stained positively with Sirius red stain for eosinophils.
- Immunohistochemistry confirmed myeloperoxidase positivity.
- Combined findings support a diagnosis of eosinophilic granulocytic sarcoma.
Implications:
- This case expands the understanding of granulocytic sarcoma origins.
- It underscores the need for comprehensive diagnostic approaches in veterinary oncology.
- Provides a reference for identifying rare eosinophilic myeloid neoplasms in animals.
