Related Experiment Video
Updated: May 21, 2026

Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
The association of body mass index and perforation of the appendix in Puerto Rican children
Carmen T Ramos1, Mariely Nieves-Plaza
1Department of Surgery, Miami Children’s Hospital, Miami, FL 33155, USA. Carmen.ramos@mch.com
Insights
Young children and those with delayed diagnosis face higher appendiceal perforation risks. This study identifies key factors for pediatric appendicitis complications in Puerto Rico.
Area of Science:
- Pediatric Surgery
- Public Health
- Epidemiology
Background:
- The Puerto Rico Department of Health has limited appendicitis data since 1996.
- Understanding appendicitis perforation risk factors is crucial for improving pediatric care.
Purpose of the Study:
- To identify factors associated with appendiceal perforation in children in Puerto Rico.
- To address the data gap in pediatric appendicitis outcomes.
Main Methods:
- Retrospective study analyzing 170 pediatric appendicitis cases from 2002-2008.
- Investigated risk factors including age, symptom duration, insurance, and hospital type.
Main Results:
- Appendiceal perforation occurred in 38% of cases.
- Significant risk factors for perforation included age under five years and symptom onset over 36 hours.
- Obesity showed a tendency towards perforation (OR: 1.5).
Conclusions:
- Younger age (under five) and delayed diagnosis (over 36 hours) are strongly associated with appendiceal perforation.
- Higher body mass index (BMI) for age percentile (>95th) also indicated a tendency for perforation.
Objective:
Puerto Rico Department of Health lacks data on appendicitis since 1996. We inquired about factors influencing perforation.
Methods:
Retrospective study of risk factors among Puerto Rican children with appendicitis from 2002-2008.
Results:
One hundred and seventy records were reviewed. Appendiceal perforation = 38%. Median age was 10 years. Risk factors for perforation were age younger than five years, onset of symptoms more than 36 hours previously, public insurance, more than two examiners, and public hospital. Obese patients had a tendency to present with perforation (OR: 1.5 (0.6-3.5)). In the multivariate analysis, the only variables that remained significant were age younger than five years (OR: 10.2 (2.2-46.7)), and onset of symptoms more than 36 hours previously (OR: 5.9 (2.3-14.7)).
Conclusion:
Age younger than five years and onset of symptoms more than 36 hours previously were associated with perforation of the appendix. Body mass index for age percentile greater than the 95th had a tendency to present with perforation.
Related Concept Videos
Appendicitis-I: Introduction
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis
Appendicitis-II: Diagnostic Studies and Management
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
