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Updated: Oct 13, 2026

An Orthotopic Resectional Mouse Model of Pancreatic Cancer
Published on: September 24, 2020
Chemotherapeutic strategies in advanced or metastatic pancreatic adenocarcinoma
Syed F Zafar1, Bassel F El-Rayes
1Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA.
Abstract:
Pancreatic cancer remains a formidable challenge for oncologists. The only curative option remains surgical resection in early-staged disease. Cytotoxic chemotherapy offers a modest survival benefit in the advanced or metastatic stage. Clinical trials of therapy have not yet yielded encouraging outcomes in advanced pancreatic cancer. In this review, we highlight recent developments in therapy focusing on trials conducted in the advanced or metastatic setting and offer insight into the challenges for future studies.
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