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Use of iron-fortified rice reduces anemia in infants
Francisco Plácido Nogueira Arcanjo1, Paulo Roberto Santos, Caio Plácido Costa Arcanjo
1Federal University of Ceara, Sobral Unit, Brazil. placidoarcanjo@yahoo.com.br
Insights
Weekly iron-fortified rice (Ultrarice®) significantly increased hemoglobin and reduced anemia prevalence in Brazilian infants. This food fortification strategy is effective for combating iron deficiency in vulnerable populations.
Area of Science:
- Public Health Nutrition
- Nutritional Epidemiology
- Pediatric Nutrition
Background:
- Iron deficiency anemia is a significant global health concern, particularly affecting infants and young children.
- Food fortification is a key strategy to address micronutrient deficiencies in populations.
- Rice is a staple food, making it a suitable vehicle for fortification.
Purpose of the Study:
- To evaluate the impact of weekly iron-fortified rice consumption on hemoglobin levels and anemia prevalence in infants.
- To compare the effects of fortified rice versus standard rice in a controlled study setting.
Main Methods:
- A cluster-randomized study involving 216 infants aged 10-23 months in Brazilian child day care centers over 18 weeks.
- The intervention group received weekly portions of iron-fortified rice (50g, 56.4mg elemental iron).
- The control group received standard rice.
Main Results:
- The intervention group showed a significant increase in mean hemoglobin levels (11.44 to 11.67 g/dL, p<0.029).
- Anemia prevalence decreased significantly in the intervention group (31.25% to 18.75%, p=0.045).
- No significant changes in hemoglobin or anemia prevalence were observed in the control group.
Conclusions:
- Weekly consumption of iron-fortified rice (Ultrarice®) is effective in improving hemoglobin levels and reducing anemia in infants.
- Rice fortification presents a viable public health intervention to combat iron deficiency in young children.
- The Number Needed to Treat (NNT) was 7, indicating a favorable therapeutic impact.
Abstract:
Food fortification is advocated to tackle iron deficiency in anemic populations. Our objective was to evaluate the impact of iron-fortified rice (Ultrarice(®)) weekly on hemoglobin and anemia levels compared with standard rice (control). This cluster-randomized study deals with infants (10-23 months) from two public child day care centers in Brazil, n = 216, in an 18 week intervention. The intervention group received individual portions of fortified rice (50 g) provided 56.4 mg elemental/Fe. For intervention center: baseline mean hemoglobin was 11.44 ± 1.07 g/dl, and after intervention 11.67 ± 0.96 g/dl, p < 0.029; for control: baseline mean hemoglobin value was 11.35 ± 4.01 g/dl, and after intervention 11.36 ± 2.10 g/dl, p = 0.986. Anemia prevalence for intervention center was 31.25% at baseline, and 18.75% at end of study, p = 0.045; for control 43.50% were anemic at baseline, and 37.1% at the end of study, p = 0.22. Number Needed to Treat was 7. Iron-fortified rice was effective in increasing hemoglobin levels and reducing anemia in infants.
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