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Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
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[Immunocorrective therapy of hematologic diseases]

V N Shabalin, L D Serova

    Vestnik Akademii Meditsinskikh Nauk SSSR
    |January 1, 1990
    PubMed

    Changes in the immunological parameters have been studied in the course of treatment with antithymocytic globulin and chemotherapeutic preparations included in the treatment protocols for aplastic anemia and acute leukemia. A possibility of determining the optimal immunocorrective agent dosage is demonstrated as related to its effect on the functioning of the immunocompetent cells in vitro.

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