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Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France

C Laurens1, A-L Michon, H Marchandin

  • 1Centre Hospitalier Régional Universitaire de Montpellier, Laboratoire de Bactériologie, Hôpital Arnaud de Villeneuve, Montpellier, France.

Antimicrobial Agents and Chemotherapy
|May 31, 2012
PubMed

Insights

This study analyzed 140 Streptococcus pseudopneumoniae isolates, finding high resistance to erythromycin and tetracycline. Pneumonia was the most common infection, particularly in patients with underlying conditions.

Area of Science:

  • Clinical Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Streptococcus pseudopneumoniae is an emerging pathogen often associated with respiratory infections.
  • Patients with underlying diseases are frequently affected by S. pseudopneumoniae.
  • Understanding antimicrobial susceptibility patterns is crucial for effective treatment.

Purpose of the Study:

  • To retrospectively analyze clinical data and antimicrobial susceptibility of Streptococcus pseudopneumoniae isolates.
  • To identify common infections and resistance trends in S. pseudopneumoniae.

Main Methods:

  • Retrospective analysis of clinical and antimicrobial susceptibility data.
  • Inclusion of 140 Streptococcus pseudopneumoniae isolates.
  • Focus on isolates from respiratory tract samples.

Main Results:

  • Pneumonia, primarily aspiration pneumonia, was the most frequent infection (27.1%).
  • High rates of decreased susceptibility and resistance were observed for erythromycin (57%) and tetracycline (43%).
  • Reduced susceptibility to penicillin was noted in 21% of isolates.

Conclusions:

  • Streptococcus pseudopneumoniae isolates frequently cause pneumonia in patients with comorbidities.
  • Significant antimicrobial resistance to erythromycin and tetracycline necessitates careful treatment selection.
  • Monitoring penicillin susceptibility is important for managing S. pseudopneumoniae infections.

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