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Updated: May 21, 2026
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Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue
Published on: November 30, 2018
Preparation and characterization of DNA aptamer based spin column for enrichment and separation of histones
Nan Shao1, Kai Zhang, Ying Chen
1State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, P. R. China.
Chemical Communications (Cambridge, England)
|May 31, 2012
Abstract:
Core histones play a critical role in the regulation of chromatin-templated biological process. Here we have developed a novel approach to enrich histone proteins based on the recognition of a specific aptamer. The method shows good selectivity toward histone proteins and is able to extract histones directly from complex whole cell lysates.
