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Increased placental phospholipase A2 activities in pre-eclampsia
1Department of Biochemistry and Chemistry, Silesian Medical School, Katowica.
Phospholipase A2 activity was significantly increased in placental homogenates from 22 patients with pre-eclampsia in comparison to placental homogenates from women with uncomplicated pregnancy. Such an abnormality may be responsible for an altered release of free arachidonic acid, thus playing a major role in the pathogenesis of this syndrome.
Phospholipase A2 activity was significantly increased in placental homogenates from 22 patients with pre-eclampsia in comparison to placental homogenates from women with uncomplicated pregnancy. Such an abnormality may be responsible for an altered release of free arachidonic acid, thus playing a major role in the pathogenesis of this syndrome.