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Related Experiment Videos

[Liver diseases and pregnancy].

A Jorde1, K R Schulz

  • 1Frauenklinik, Klinikums Berlin-Buch.

Zentralblatt Fur Gynakologie
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Hepatitis in pregnancy requires hospitalization for 1.4% of women, often indicating diminished placental function. This can lead to low birth weight infants and increased obstetric operations.

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Area of Science:

  • Hepatology
  • Obstetrics
  • Perinatology

Background:

  • Viral hepatitis during pregnancy presents diagnostic and management challenges.
  • Limited data exists on the impact of suspected viral hepatitis on pregnancy outcomes.

Purpose of the Study:

  • To investigate the frequency of viral hepatitis hospitalization during pregnancy.
  • To evaluate the association between suspected viral hepatitis and pregnancy complications.
  • To discuss diagnostic approaches and pregnancy management in these cases.

Main Methods:

  • Retrospective analysis of 161,674 pregnant women.
  • Identification of hospitalizations for suspected viral hepatitis.
  • Assessment of diagnostic confirmation rates (histology).

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  • Evaluation of infant birth weight and obstetric operation rates.

    • Main Results:

    • A hospitalization rate of 1.4%o for suspected viral hepatitis was observed.
    • Histological confirmation of viral hepatitis was achieved in 18.5% of cases.
    • Low birth weight infants occurred in 24.2% of cases.
    • Obstetric operations were performed in 13.4% of cases, suggesting diminished placental function.

    Conclusions:

    • Suspected viral hepatitis in pregnancy is associated with adverse outcomes, including low birth weight and increased need for obstetric interventions.
    • These outcomes suggest impaired placental function in pregnancies affected by liver disease.
    • Further research is needed to optimize diagnostics and management strategies for pregnant women with liver diseases.