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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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The therapeutic future in headache.

Alan M Rapoport1

  • 1The David Geffen School of Medicine at UCLA, 239 South Orange Drive, Los Angeles, CA 90036, USA. alanrapoport@gmail.com

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 31, 2012
PubMed
Summary
This summary is machine-generated.

New acute care treatments for migraine and cluster headache are emerging, focusing on faster, more efficient therapies with fewer side effects. Several novel medications and delivery systems are under investigation for improved headache management.

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Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Headaches encompass diverse types with varied treatments.
  • Current acute migraine care includes triptans and NSAIDs.
  • OnabotulinumtoxinA is approved for chronic migraine prevention.

Purpose of the Study:

  • To review new and future acute care treatments for migraine.
  • To discuss emerging treatments for cluster headache.
  • To highlight advancements aiming for faster, safer, and more effective headache therapies.

Main Methods:

  • Review of current and investigational acute care medications for migraine.
  • Discussion of novel delivery systems for existing drugs.
  • Overview of potential treatments for cluster headache.

Main Results:

  • Several new acute migraine treatments are in development, including CGRP antagonists and novel triptan delivery methods.
  • Investigational treatments for cluster headache include new preventative nasal solutions and neuromodulation.
  • The goal is to improve upon existing treatments' speed, usability, efficiency, and safety profiles.

Conclusions:

  • The pipeline for acute headache treatments shows promise for improved patient outcomes.
  • Future therapies aim to address unmet needs in migraine and cluster headache management.
  • Advancements include new drug targets, delivery systems, and neuromodulation techniques.