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Intraocular pressure elevation after Descemet's stripping endothelial keratoplasty
Naoki Ozeki1, Kenya Yuki, Daisuke Shiba
1Department of Ophthalmology, Keio University School of Medicine, Shinanomachi 35, Shinjuku-ku, Tokyo, Japan. n_ozeki@2002.jukuin.keio.ac.jp
Japanese Journal of Ophthalmology
|May 31, 2012
Summary
Intraocular pressure (IOP) elevation occurred in 16.7% of patients after Descemet's stripping endothelial keratoplasty (DSEK). Higher preoperative IOP was a risk factor, necessitating careful follow-up for these patients.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Glaucoma Research
Background:
- Descemet's stripping endothelial keratoplasty (DSEK) is a common procedure for corneal diseases.
- Postoperative intraocular pressure (IOP) elevation is a potential complication following ocular surgeries.
- Understanding the incidence and risk factors of IOP elevation after DSEK is crucial for patient management.
Purpose of the Study:
- To determine the incidence of intraocular pressure (IOP) elevation after Descemet's stripping endothelial keratoplasty (DSEK).
- To identify associated clinical findings and risk factors for post-DSEK IOP elevation.
Main Methods:
- A single-center retrospective study included 48 eyes of 46 patients who underwent DSEK.
- IOP elevation was defined as IOP > 21 mmHg for at least two months, requiring glaucoma medication or surgery.
- Patients with pre-existing glaucoma or pre-operative glaucoma medication were excluded.
Main Results:
- The incidence of IOP elevation after DSEK was 16.7%.
- Eight patients required glaucoma therapy post-DSEK, with elevations diagnosed 2-10 months after surgery.
- Preoperative IOP was identified as a significant risk factor for postoperative IOP elevation.
Conclusions:
- IOP elevation is a notable postoperative complication of DSEK.
- Patients without prior glaucoma but with elevated preoperative IOP require vigilant monitoring after DSEK.
- This highlights the importance of assessing and managing preoperative IOP in DSEK candidates.
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