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Updated: May 21, 2026
11:39
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Considerations when initiating psoriasis patients on biologic therapy
1Mount Sinai Medical Center, New York, NY 10029, USA. joshzeichner@gmail.com
Journal of Drugs in Dermatology : JDD
|May 31, 2012
Summary
This paper reviews targeted immunologic therapies, known as biologic agents, for treating psoriasis. It focuses on these advanced treatments over traditional systemic options like cyclosporine and methotrexate.
Area of Science:
- Immunology
- Dermatology
- Pharmacology
Background:
- Psoriasis is a chronic autoimmune condition requiring systemic treatment.
- Traditional systemic therapies include immunosuppressants (cyclosporine, methotrexate) and oral retinoids (acitretin).
Purpose of the Study:
- To focus on the application of targeted immunologic therapies for psoriasis management.
- To provide an overview of biologic agents used in psoriasis treatment.
Main Methods:
- Literature review of systemic therapies for psoriasis.
- Specific focus on biologic agents and their mechanisms.
- Comparison with traditional systemic treatments.
Main Results:
- Biologic agents represent a targeted approach to psoriasis therapy.
- These agents modulate specific immune pathways involved in psoriasis pathogenesis.
- Effectiveness and safety profiles of various biologic agents are considered.
Conclusions:
- Biologic agents offer a distinct therapeutic strategy for psoriasis.
- Understanding targeted immunotherapies is crucial for effective psoriasis management.
- Further research into novel biologic agents continues to advance treatment options.
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