The specific characteristics in children with obstructive sleep apnea and cor pulmonale
Pi-Chang Lee1, Betau Hwang, Wen-Jue Soong
1Division of Pediatric Cardiology, Departments of Pediatrics, National Yang-Ming University and Taipei Veterans General Hospital, No 201 Sec 2, Shih-Pai Road, Taipei 112, Taiwan. pichang lee@yahoo.com
Insights
Pediatric obstructive sleep apnea (OSA) with cor pulmonale presents unique clinical and hemodynamic features. Adenotonsillectomy effectively improved pulmonary arterial pressure in these children.
Area of Science:
- Pediatric Cardiology
- Sleep Medicine
- Pulmonology
Background:
- Obstructive sleep apnea (OSA) affects 1-2% of children.
- Cor pulmonale, a complication of OSA, requires further investigation in pediatric cases.
Purpose of the Study:
- To examine clinical and hemodynamic differences in pediatric patients with OSA, comparing those with and without cor pulmonale.
Main Methods:
- A cohort of 30 children diagnosed with OSA was studied.
- Five children had co-existing cor pulmonale, while 25 had OSA alone.
Main Results:
- Children with OSA and cor pulmonale exhibited higher arousal indices, lower oxygen saturation, and more bradycardia events.
- Adenotonsillectomy in the 5 patients with OSA and cor pulmonale led to a significant reduction in pulmonary arterial pressure.
Conclusions:
- Pediatric OSA patients with cor pulmonale display distinct clinical and hemodynamic profiles compared to those without.
- Adenotonsillectomy proved highly effective in managing both OSA and associated cor pulmonale in pediatric patients.
Background:
The prevalence of obstructive sleep apnea (OSA) in the pediatric population is currently estimated at 1-2% of all children. The purpose of this study was to investigate the clinical and hemodynamic characteristics in pediatric patients with cor pulmonale and OSA.
Methods:
Thirty children with the diagnosis of OSA were included. These patients consisted of 26 male and 4 female children with a mean age of 7 ± 4 years old. Five of those children were found to be associated with cor pulmonale, and 25 had OSA but without cor pulmonale.
Results:
The arousal index was much higher in children with OSA and cor pulmonale. The children with OSA and cor pulmonale had much lower mean and minimal oxygen saturation and a higher incidence of bradycardia events. All 5 patients with OSA and cor pulmonale underwent an adenotonsillectomy, and the pulmonary arterial pressure dropped significantly after the surgery.
Conclusion:
This study demonstrated that the OSA pediatric patients with cor pulmonale had the different clinical manifestations and hemodynamic characteristics from those without cor pulmonale. The adenotonsillectomy had excellent results in both the OSA pediatric patients with and without cor pulmonale.
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