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Updated: May 21, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
Published on: December 16, 2013
Synthesis, characterization, and evaluation of five coordinated copper(II) complexes as antibacterial, artificial
M N Patel1, D S Gandhi, P A Parmar
1Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar, Gujarat, India. jeenen@gmail.com
Abstract:
The copper(II) complexes with ciprofloxacin (CFLH), levofloxacin (LFLH), norfloxacin (NFLH), and neutral bidentate ligands have been synthesized and characterized. The complexes have been evaluated for their antibacterial activity against selective species. Complexes have been also checked for their interacting behavior with DNA, and were found to have two different modes of interaction, classical and partial intercalation. Tested complexes were found to be better antioxidants with their IC(50) values ranging from 0.51 to 0.97 μM.
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