Related Experiment Video
Updated: May 21, 2026

Image-based Flow Cytometry Technique to Evaluate Changes in Granulocyte Function In Vitro
Published on: December 26, 2014
How do we collect better granulocyte?
Tülay Karaağaç Akyol1, Yahya Büyükaşık, Salih Aksu
1Hacettepe University Hospital, Blood Center and Apheresis Unit, F-06100 Altındağ-Ankara, Turkey. drtulaykaraagac@yahoo.com
Abstract:
We studied retrospectively the factors affecting the product quality in 459 donor granulocyte apheresis procedures from 420 donors for 71 neutropenic patients from 2004 to 2010 in a single center. The counts of the granulocyte and platelet collected were measured to evaluate the product quality. The data was analyzed to determine a possible relationship between product quality and several parameters including gender, preleukapheresis neutrophil count, type of anticoagulation and separator type and mode of the apheresis system. We found that collection of better granulocyte is possible from a donor in a single procedure by changing anticoagulation type and separator mode during apheresis.
Related Concept Videos
Classification of Leukocytes
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
Differentiation of Common Myeloid Progenitor Cells

