Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Craniocerebral involvement in lymphoma.

J D Correale1, D A Monteverde, J A Bueri

  • 1Division of Neurology, José María Ramos Mejía Hospital, Buenos Aires, Argentina.

Arquivos De Neuro-Psiquiatria
|September 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microglia-derived extracellular vesicles in homeostasis and demyelination/remyelination processes.

Journal of neurochemistry·2023
Same author

[Neuropsychological study of 12 patients with pure degenerative cerebellar disease].

Revista de neurologia·2005
Same author

Undulating toe movements in brain death.

European journal of neurology·2004
Same author

Insomnia associated with thalamic involvement in E200K Creutzfeldt-Jakob disease.

Neurology·2002
Same author

Lazarus' sign in brain death.

Movement disorders : official journal of the Movement Disorder Society·2000
Same author

Spontaneous and reflex movements in brain death.

Neurology·2000
Same journal

Prevalence and predictors of low bone mineral density in Myasthenia gravis.

Arquivos de neuro-psiquiatria·2026
Same journal

Hypochondriasis, somatic amplification, and pain beliefs in patients with medication overuse headache.

Arquivos de neuro-psiquiatria·2026
Same journal

Ozzy Osbourne and Parkinson's disease: from darkness to awareness.

Arquivos de neuro-psiquiatria·2026
Same journal

The weight of genotype on the clinical presentation of COQ7-related hereditary motor axonal neuropathy: a case series and literature review.

Arquivos de neuro-psiquiatria·2026
Same journal

Rituximab as a sustainable high-efficacy solution for multiple Sclerosis in Brazil.

Arquivos de neuro-psiquiatria·2026
Same journal

Reply to: "Sleep quality is influenced by multiple factors and cannot be reduced to the volume of pineal gland calcification".

Arquivos de neuro-psiquiatria·2026
See all related articles

Lymphoma can spread to the brain and central nervous system (CNS), with risk factors including advanced disease and specific lymphoma types. Early detection and treatment are crucial for improving outcomes in these complex cases.

Area of Science:

  • Neurology
  • Oncology
  • Pathology

Background:

  • Lymphoma, a cancer of the lymphatic system, can infiltrate the central nervous system (CNS), including the brain.
  • Craniocerebral involvement in lymphoma presents diagnostic and therapeutic challenges, impacting patient prognosis.

Purpose of the Study:

  • To investigate the incidence, risk factors, clinical presentation, diagnostic methods, and outcomes of lymphomatous craniocerebral infiltration.
  • To analyze associated CNS complications such as hemorrhage and infection in lymphoma patients.

Main Methods:

  • Retrospective analysis of 989 lymphoma patients.
  • Review of clinical data, diagnostic imaging (CT-scan), and autopsy findings.
  • Correlation of pathological findings with treatment complications.

Related Experiment Videos

Main Results:

  • Lymphomatous craniocerebral infiltration occurred in 5.3% of patients, with advanced stage, specific histological types, bone marrow involvement, and prior chemotherapy as key risk factors.
  • Computed tomography (CT) scans were effective for detecting parenchymal infiltration but less so for meningeal disease.
  • Mean survival for meningeal infiltration was 4.3 months with combined therapy; CNS infections and intracranial hemorrhages were observed complications.

Conclusions:

  • Craniocerebral infiltration is a significant complication of lymphoma, requiring vigilant monitoring and tailored treatment strategies.
  • Prompt diagnosis and multimodal therapy can improve survival, though CNS complications remain a concern.
  • Treatment-related pathological changes in the brain warrant consideration in managing lymphoma patients.